Patient-derived cell (PDC) models bridge the gap between conventional cancer lines that do not faithfully replicate clinical responses and costly and time-consuming patient-derived xenograft (PDX) models. To enable large scale drug sensitivity testing in PDCs, we have developed a phenotypic High Content Imaging (HCI) platform with a multitude of endpoint readouts. These can be applied to assess biomarkers of response, potential combination therapy synergies and the modelling of clinical trial participants.
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