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Dr Griffiths’ career started out in academia and gave him many years postdoctoral experience. Subsequently, he took a challenging role in industry in the field of Systems Biology. Working in this field led him to specialise in High Content Analysis, which is highly compatible with generating the very rich data sets required for Systems Biology. Promotion to a position central to the High Content Screening facility within AstraZeneca provided him with a deep understanding of its usage and benefits across a large number of diverse projects. He gained hands on experience in a whole array of algorithms for analysing images and now has expert knowledge in this area. His desire was to form his own company based around these skills and so he left AstraZeneca to become Chief Scientific Officer and co-founder of Imagen Therapeutics (formerly Imagen Biotech). Since working for Imagen Therapeutics, Gareth has developed many new and exciting phenotypic screening assays, including a detailed morphology assay that can successfully cluster chemotherapeutic compounds. Gareth is also the creator of the main assay we now use to measure the cell death response of primary patient samples. This assay is not antibody-based, meaning that it can be conducted in both 2D and 3D culture modes.

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